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Hypoglycemic Effect of Kyllinga Triceps in STZ Induced Diabe | 26454

ஜர்னல் ஆஃப் நீரிழிவு & மெட்டபாலிசம்

ஐ.எஸ்.எஸ்.என் - 2155-6156

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Hypoglycemic Effect of Kyllinga Triceps in STZ Induced Diabetic Rats

Lal VK, Gupta PP and Pandey Awanish

Kyllinga triceps is an Indian medicinal plant demonstrated to exert multiple pharmacological effects. In light of traditional claim of the plant in treatment of diabetes, the present study was carried out to evaluate the hypoglycemic activity of the plant in Streptozotocin (STZ) induced diabetic rats. The diabetic rats were given Kyllinga triceps extract (KTE, 100mg/kg & 200mg/kg) and Glibenclamide (0.5mg/kg) for 28 days. The effects of both treatments on body weight and blood glucose were assessed. Both doses of extract and Glibenclamide showed significant hypoglycemic activity in acute and sub acute study. Body weight of extract and glibenclamide treated rats were maintained during the study period Where as body weight of untreated rats had gone down. The result obtained from the study scientifically proved the folkloric use of Kyllinga triceps as hypoglycemic agent. Thus the plant can be key contributor in treatment of Diabetes.